Tretinoin is available in 10-mg capsules for oral administrationin the treatment of APL. The mechanism of action involvespassive diffusion through the cell membrane andthen movement to the nucleus where it interacts with theretinoic acid receptor (RAR) portion of the PML-RAR fusionprotein. Binding of tretinoin allows the cell to differentiateand has also been shown to result in the destruction ofthe PML-RAR fusion protein. Resistance to tretinoin isproblematic and associated with an increase in cellularretinoic acid-binding proteins (CRAPBs) located in the cytosol.
| Appearance | yellow powder |
|---|---|
| Storage | Stored in a clean, cool, dry area; keep away from strong, direct light |
| Shelf Life | 2 years |
| Specifications | 98% |
Tretinoin is available in 10-mg capsules for oral administrationin the treatment of APL. The mechanism of action involvespassive diffusion through the cell membrane andthen movement to the nucleus where it interacts with theretinoic acid receptor (RAR) portion of the PML-RAR fusionprotein. Binding of tretinoin allows the cell to differentiateand has also been shown to result in the destruction ofthe PML-RAR fusion protein. Resistance to tretinoin isproblematic and associated with an increase in cellularretinoic acid-binding proteins (CRAPBs) located in the cytosol.
Function :
(1) Applies to abnormal tyshiyongyupe of acne, fish phosphorus disease and abnormal psoriasis.
(2) Resistance to abnormal skin drugs.
(3) Tretinoin mainly affects the growth of bones and epithelial metabolism, can promote epithelial cell proliferation and updates, and can inhibit the proliferation and differentiation of keratinocytes, so hyperkeratosis can be back to normal. Therefore many complete or incomplete keratosis, hyperkeratosis of diseases have a certain therapeutic effect, treat a variety of skin diseases. Tretinoin is mainly used in the treatment of psoriasis, ichthyosis, follicular keratosis, acne, lichen planus, verrucous epidermal nevus, impetigo, vitiligo, lichen psoriasis, the face of pityriasis alba, etc.
Application : Cosmetics and pharmaceutical .
1.High Product Purity: These facilities employ advanced extraction techniques, such as supercritical fluid extraction, solvent extraction, or steam distillation, to obtain highly pure plant extracts. The rigorous purification processes ensure the removal of impurities, resulting in high-quality extracts with consistent composition and potency.
2.Diverse Product Range: We can process a wide variety of plant materials, allowing for the production of an extensive range of botanical extracts. Different plants possess unique chemical compositions, providing an opportunity to extract various bioactive compounds, including essential oils, polyphenols, alkaloids, and flavonoids, each with its own potential applications and benefits.
3.Customization and Formulation: These facilities offer the flexibility to customize and formulate botanical extracts according to specific requirements. Manufacturers can tailor the concentration, composition, and bioactive profile of extracts to meet the needs of their target markets and applications. This versatility enables the creation of innovative products with enhanced functionalities.
4.Quality Control and Standards: We adhere to stringent quality control measures and industry standards to ensure the safety, efficacy, and consistency of their products. This includes rigorous testing for contaminants, heavy metals, pesticides, and microbial organisms. Implementing quality control protocols helps maintain product integrity and regulatory compliance.
5.Research and Development: We often collaborate with academic institutions and research organizations to explore the potential applications of plant extracts and discover new bioactive compounds. This continuous research and development foster innovation and contribute to the expanding knowledge of the therapeutic, nutritional, and functional properties associated with botanical extracts.
6.Customer Support: A key advantage of after-sales service is providing timely and efficient customer support. This includes addressing customer inquiries, resolving issues, and providing technical assistance. By offering responsive and knowledgeable support, businesses can enhance customer satisfaction and loyalty.
7. Free Sample : Low value products ,we offer 10-50g free sample to test，and the most of two kinds products for one time.
8.Delivery time :Usually ,the delivery time less than one week for the quantity less than 500kg , About ten days for the order quantity more than 500kg.
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